Health

Maddrey Discriminant Function Calculator

Assess alcoholic hepatitis severity and steroid indication.

Patient's PT (seconds)

Control PT (seconds)

Total Bilirubin (mg/dL)

Discriminant Function—

Severity—

Recommendation—

MDF = 4.6 × (PT − PT_control) + Bilirubin
≥32: Severe — consider prednisolone 40 mg/day × 28 days